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KMID : 0352519810180020357
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Korea Univercity Medical Journal
1981 Volume.18 No. 2 p.357 ~ p.364
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The Clinical Study on the Serum Vitamin B_(12) Level in Primary Chronic Atrophic Gastritis
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Abstract
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Author has measured RBC count, hemoglobin level and hematocrit value including serum vitamin B12 level on 106 patients with primary chronic atrophic gastritis confirmed by the gastrofiberscopy and tissue biopsy visiting to the Department of Gastroenterology, Korea University Hospital from December, 1979 to October, 1980 and tried to establish the pathogenetic role of primary chronic atrophic gastritis in developing pernicious anemia.
RBC count, hemoglobin level and hematocrit value which signify hematologic guide-posts of anemia showed normal ranges; the serum vitamin Bit levels appeared normal ranges with its MS.D. of 561.4-176.6 pg/dl in all cases with primary chronic atrophic gastritis.
The most common site of the involvement of chronic atrophic gastritis is antrum and body by showing 50.9 per cent in its frequency. The second most common site of the involvement consists in the entire wall of the stomach of antrum, body and fundus by 41.6 per cent.
It is concluded that the primary chronic atrophic gastritis does not supposedly play a role in developing pernicious anemia. Active studies concerning the relationship between chronic atrophic gastritis and pernicious anemia have to be performed immunologically in the future.
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